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Vitamins Vitamin B12 and folate (or folic acid) are under investigation for beneficial effects on fertility

Eryilmaz, E., Shah, N

Hormonal changes that initially suppress appetite may diminish over time, whilst anatomical alterations to the gastrointestinal tract can gradually accommodate larger food volumes

Clinical Benefits: Supports red blood cell formation and helps prevent megaloblastic anaemia Essential for neurological function and nerve tissue health Plays a key role in DNA synthesis and cell metabolism Supports cognitive function, concentration, and mood regulation Assists in the conversion of homocysteine, supporting cardiovascular health Helps address fatigue and weakness associated with B12 deficiency For patients presenting with deficiency, a loading protocol is typically recommended: weekly injections for three weeks, followed by monthly injections for three months, then a maintenance injection every three months

Supplementary Table 4

This regulatory distinction is important because supplements are not subject to the same rigorous testing, quality control, and safety monitoring as prescription pharmaceuticals